Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... Authors: Saran, S, Majdi Yazdi, M, Sanders, D.A.R. Deposit date: 2020-11-02 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.84 Å) Cite: H59 PLAYS THE MOST VITAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS ENZYME To Be Published

来自空肠弯曲杆菌（C.jejuni）的二氢二吡啶甲酸合酶（Dihydrodipicolinate synthase, DHDPS）H59N突变体，其活性位点结合丙酮酸，别构位点结合R,R-双赖氨酸。描述符：(2R,5R)-2,5-二氨基-2,5-双(4-氨基丁基)己二酸、1,2-乙二醇（1,2-ETHANEDIOL）、4-羟基四氢二氢二吡啶甲酸合酶（4-hydroxy-tetrahydrodipicolinate synthase）等…… 作者：Saran, S、Majdi Yazdi, M、Sanders, D.A.R.。存入日期：2020-11-02；发布日期：2021-11-17；最后修改日期：2023-11-29。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.84埃（Å））。引用说明：H59位点在Cj.DHDPS酶的别构抑制信号传递中发挥至关重要的作用，待发表。