Supplementary dataset 6 - The effects of model complexity and size on metabolic flux distribution and control. Case study in Escherichia coli.
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6th part of Supplementary dataset 1-15: contains populations of 50'000 control coefficients (Metabolic Control Analysis) for three models D1, D2 and D3 of different network size. These populations of control coefficients were used to study the effects of model complexity - in terms of network size - on the conclusions drawn from MCA. A metric for measuring the sensitivity of MCA control coefficients to these structural changes was proposed.
补充数据集1-15的第6部分:收录了针对三种不同网络规模的模型D1、D2、D3的50000组控制系数种群,相关内容依托代谢控制分析(Metabolic Control Analysis)构建。上述控制系数种群被用于研究以网络规模为维度的模型复杂度对代谢控制分析(MCA)所得结论的影响。本研究同时提出了一种可量化度量MCA控制系数对这类结构变化敏感性的指标。
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Zenodo创建时间:
2021-03-05



