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Major laboratory strain of Salmonella typhimurium. Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

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NIAID Data Ecosystem2026-03-06 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA241
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Salmonella enterica subsp. enterica serovar typhimurium strain LT2. This strain was first isolated in the 1940s by Lilleengen, and typed based on phage sensitivity. It became the principle laboratory strain and many important biochemical and genetic experiments were performed using this strain, including classical phage transduction studies. LT2 contains a plasmid, pSLT, that encodes additional virulence functions. Numerous prophages, some of which contain virulence genes, are inserted into the chromosome of LT2 as compared to related Salmonella.

鼠伤寒沙门氏菌LT2菌株(Salmonella enterica subsp. enterica serovar Typhimurium strain LT2)。该菌株于1940年代由Lilleengen首次分离,并通过噬菌体敏感性试验完成分型。其随后成为核心实验室模式菌株,诸多重要的生化与遗传学实验均以该菌株为实验材料开展,其中包括经典的噬菌体转导研究。LT2菌株携带pSLT质粒,该质粒编码额外的毒力相关功能。与近缘沙门氏菌相比,LT2的染色体中整合了多种前噬菌体,其中部分前噬菌体携带有毒力基因。
创建时间:
2003-02-25
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