NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CARDIA)

This sub-study http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000399GO-ESP HeartGO_CARDIA contains genotype derived from sequence data and selected phenotype of subjects available from the http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000399study. Summary level phenotypes for the NHLBI CARDIA Cohort study participants can be viewed at the top-level study page http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000285CARDIA Cohort. Individual level phenotype data and molecular data for all CARDIA Cohort top-level study and sub-study are available by requesting Authorized Access to the NHLBI CARDIA Cohort http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000285study. The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the... (for more see dbGaP study page.)

本子研究http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000399GO-ESP HeartGO_CARDIA 的基因型数据源自测序数据，包含可从研究http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000399study 获取的受试者筛选表型信息。美国国家心肺血液研究所（National Heart, Lung, and Blood Institute, NHLBI）CARDIA队列研究参与者的汇总级表型数据，可在顶层研究页面http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000285CARDIA Cohort 查看。所有CARDIA队列顶层研究及子研究的个体级表型数据与分子数据，需通过申请获得美国国家心肺血液研究所CARDIA队列的授权访问权限后方可获取，相关访问链接为http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000285study。美国国家心肺血液研究所"大机遇"外显子组测序项目（Grand Opportunity Exome Sequencing Project, GO-ESP）是美国复苏法案资助下NHLBI的标志性项目，旨在识别编码区域（外显子，exons）内的遗传变异……（更多详情请参见基因型与表型数据库（Database of Genotypes and Phenotypes，dbGaP）研究页面）