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Diagnostic and Predictive Value of Hematologic Parameters for Hyperaldosteronism in Hypertensive Patients

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Zenodo2025-06-06 更新2026-05-26 收录
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This dataset supports a retrospective observational study investigating the diagnostic and predictive value of hematologic parameters in primary aldosteronism (PA) screening. It includes anonymized data from 169 hypertensive patients evaluated between January 2021 and December 2023. Variables include plasma aldosterone concentration (PAC), plasma renin activity (PRA), aldosterone-to-renin ratio (ARR), and hemogram-derived markers such as white blood cells, neutrophils, lymphocytes, platelets, and calculated indices (NLR, PLR, SII). The findings revealed a significant association between PAC and platelet count (PLT), suggesting that PLT may serve as a supplementary biomarker for detecting hyperaldosteronism.

本数据集可支撑一项回顾性观察研究,该研究旨在探讨血液学参数在原发性醛固酮增多症(primary aldosteronism, PA)筛查中的诊断与预测价值。数据集纳入了2021年1月至2023年12月期间接受评估的169例高血压患者的匿名化数据,所涵盖的变量包括血浆醛固酮浓度(plasma aldosterone concentration, PAC)、血浆肾素活性(plasma renin activity, PRA)、醛固酮肾素比值(aldosterone-to-renin ratio, ARR),以及血常规衍生标志物:白细胞、中性粒细胞、淋巴细胞、血小板,与相关计算指标(中性粒细胞与淋巴细胞比值NLR、血小板与淋巴细胞比值PLR、系统性免疫炎症指数SII)。研究结果显示,PAC与血小板计数(platelet count, PLT)存在显著相关性,提示PLT可作为醛固酮增多症检测的补充生物标志物。

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Zenodo
创建时间:
2025-06-06
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