Antibodies against Leptospira spp. in bovine serum samples from several Brazilian states analyzed in the period from 2007 to 2015

ABSTRACT Bovine leptospirosis assumes great economic importance since it affects several production aspects. Therefore, knowledge about the occurrence and distribution of this disease is fundamental to adopt the correct prevention measures. The present study aimed to evaluate the frequency of anti-Leptospira spp. antibodies in 24,483 bovine serum samples received between 2007 to 2015 from 21 Brazilian states. Of these, 8,643 (35.3%) were reagents in the microscopic agglutination test to one or more serovars of Leptospira spp. The most frequent serovars were Wolffi (61.47%), Tarassovi (9.62%) and Pomona (7.20%). Hardjo serovar presented a prevalence of 6.27%. Among the 21 states analyzed, the State of Pernambuco had the highest frequency with 88.24% and the State of São Paulo was the origin of the largest number of analyzed samples (13,838), with a frequency of 31.54% of reagents. The results demonstrate a high exposure to several serovars of Leptospira spp. in bovine species in Brazilian states, showing the importance of adopting prophylactic measures in order to reduce the risk of infection in this specie.

摘要：牛钩端螺旋体病（Bovine leptospirosis）具有显著的经济危害性，可对畜牧业多项生产环节造成负面影响。因此，掌握该疾病的发生与分布特征，是制定科学防控措施的必要前提。本研究针对2007年至2015年间收到的、采自巴西21个州的24483份牛血清样本，开展抗钩端螺旋体属（Leptospira spp.）抗体阳性检出率的评估。结果显示，其中8643份样本（占总样本量的35.3%）在显微凝集试验（microscopic agglutination test）中对一种或多种钩端螺旋体血清型呈阳性反应。检出频率最高的三种血清型依次为沃尔夫（Wolffi，61.47%）、塔拉索夫（Tarassovi，9.62%）与波莫纳（Pomona，7.20%）；哈德乔（Hardjo）血清型的检出率为6.27%。在21个受检州中，伯南布哥州（Pernambuco）的阳性检出率最高，达88.24%；圣保罗州（São Paulo）的送检样本数量最多，共计13838份，其阳性检出率为31.54%。本研究结果表明，巴西各州市的牛群普遍暴露于多种钩端螺旋体血清型，提示需采取针对性的预防措施以降低该畜群的感染风险。