Repression of Human and Mouse Brain Inflammaging Transcriptome by Broad Gene Body Histone Hyperacetylation (RNA-seq). Repression of Human and Mouse Brain Inflammaging Transcriptome by Broad Gene Body Histone Hyperacetylation (RNA-seq)

RNA-seq data of human prefrontal cortex and mouse brain during aging and/or SAHA treatment were generated. Overall design: For RNA extraction, human brain samples with similar age were pooled together, mouse brain samples were extract individually. After RNA extraction by TRIzol, library construction and high-throughput sequencing was done.

本数据集生成了衰老及/或辛二酰苯胺异羟肟酸（SAHA）处理条件下，人前额叶皮层（human prefrontal cortex）与小鼠大脑的RNA测序（RNA-seq）数据。实验设计概述：RNA提取环节中，将年龄匹配的人脑样本进行混样处理，小鼠脑样本则单独提取RNA。采用TRIzol法完成RNA提取后，开展文库构建与高通量测序工作。