RADx-UP Supplement-Vaccine Hesitancy and Uptake

The Georgia Center for Diabetes Translation Research Center (P30DK111024) proposes to collaborate with our RADx-UP Diabetes rural community partner and utilizing locally developed and tested Georgia CEAL (1OT2HL156812-01/16-312-0217571-66105L) COVID-19 communication materials to enhance COVID-19 testing in addition to vaccine confidence and uptake in underserved populations most severely affected by COVID-19 disease (i.e., African Americans and Latinos with diabetes, prediabetes, and their household contacts [“bubble”]). The proposed 1-year project will implement and evaluate a brief Community Health Worker (CHW) intervention through the Albany Area Primary Health Care, a rural Federally Qualified Health Center (FQHC). The primary goal of this study is to maximize effective outreach, education, and communication through CHWs in order to facilitate improved COVID-19 vaccine confidence and uptake in underserved and vulnerable communities. CHWs will be deployed to the homes of adults with increased risk of morbidity and mortality (i.e., African Americans or Latinos with uncontrolled diabetes or prediabetes, age <50 years, and non-COVID-19 vaccinated) in order to educate them about diabetes, COVID-19 and related vaccines. Health assessments, including blood glucose measurement, will be conducted on the indexed patient and offered to all other adult family members in the household (i.e., “bubble”). Adults with Type 2 diabetes likely live in households with other adults who have or are at increased risk for diabetes (i.e., prediabetes and obesity). It is expected that they will also share similar COVID-19 exposure risk. The specific aims are to: 1) Evaluate a community-driven education program to increase and enhance COVID-19 vaccine confidence and uptake in individuals with uncontrolled diabetes and their families (i.e., their “bubble”) and 2) Evaluate a community-driven education program to improve diabetes self-management behaviors and related outcomes (e.g., blood glucose) in individuals with uncontrolled diabetes in rural, Southwest Georgia.

佐治亚州糖尿病转化研究中心（Georgia Center for Diabetes Translation Research Center，项目编号P30DK111024）拟与RADx-UP糖尿病乡村社区合作伙伴开展合作，依托本地开发并验证的佐治亚州CEAL（1OT2HL156812-01/16-312-0217571-66105L）新冠病毒（COVID-19）宣传材料，在受新冠疫情冲击最严重的弱势人群——即合并糖尿病、前驱糖尿病的非裔与拉丁裔人群及其家庭接触者“防护圈”——中，同步提升新冠病毒检测率与疫苗接种信心、接种依从性。本为期1年的拟议项目将通过奥尔巴尼地区初级卫生保健中心（Albany Area Primary Health Care，一家乡村联邦合格健康中心Federally Qualified Health Center, FQHC），实施并评估一项简短的社区健康工作者（Community Health Worker, CHW）干预方案。本研究的首要目标是依托社区健康工作者开展高效的社区推广、健康教育与信息传播，以改善弱势及脆弱社区人群的新冠疫苗接种信心与接种依从性。社区健康工作者将入户走访发病与死亡风险升高的成人群体：即合并未控制糖尿病或前驱糖尿病、年龄小于50岁且未接种新冠疫苗的非裔或拉丁裔人群，为其讲解糖尿病、新冠病毒及相关疫苗的相关知识。研究人员将为索引患者开展健康评估，包括血糖检测，并为家庭中所有其他成年成员（即其“防护圈”）提供该评估服务。2型糖尿病患者大概率与其他存在糖尿病患病风险（即前驱糖尿病与肥胖）的成年成员同住一户，且二者的新冠病毒暴露风险也较为相似。本研究的具体研究目标为：1）评估一项社区主导的教育项目，以提升未控制糖尿病患者及其家庭（即其“防护圈”）的新冠疫苗接种信心与接种率；2）评估一项社区主导的教育项目，以改善佐治亚州西南部乡村地区未控制糖尿病患者的糖尿病自我管理行为及相关结局指标（如血糖水平）。