Structure of neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
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Structure of neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) Descriptor: 6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]bis(4-methylpyridin-2-amine), ACETATE ION, CHLORIDE ION, ... Authors: Li, H, Delker, S.L, Poulos, T.L. Deposit date: 2010-05-25 Release date: 2011-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase . Biochemistry, 49, 2010
与6,6'-(2,2'-(5-氨基-1,3-亚苯基)双(乙烷-2,1-二基))双(4-甲基吡啶-2-胺)结合的神经元型一氧化氮合酶(neuronal nitric oxide synthase)D597N/M336V突变体血红素结构域(heme domain)的结构。配体描述:6,6'-[(5-氨基苯-1,3-二基)二乙烷-2,1-二基]双(4-甲基吡啶-2-胺)、乙酸根离子(acetate ion)、氯离子(chloride ion)……作者:Li, H、Delker S.L、Poulos T.L.。提交日期:2010-05-25;发布日期:2011-02-09;最后修改日期:2023-09-06。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2 埃。引用文献:《锌在神经元型一氧化氮合酶亚型选择性抑制剂结合中的作用》,《生物化学(Biochemistry)》,第49卷,2010年
创建时间:
2010-05-25



