CCDB_4065.jpg

Triple labeled confocal image of hippocampal area CA1 of a transgenic mouse engineered to overexpress alpha synuclein under the Thy-1 promotor, immunolabeled for mGluR5 (red), alpha synuclein (green) and counterstained with DAPI (blue) to reveal cell nuclei.

本数据集为经基因工程改造、在Thy-1启动子（Thy-1 promotor）调控下过表达α-突触核蛋白（alpha synuclein）的转基因小鼠海马CA1区的三重标记共聚焦显微图像。该样本通过免疫标记技术分别对代谢型谷氨酸受体5（mGluR5，信号呈红色）与α-突触核蛋白（alpha synuclein，信号呈绿色）进行标记，并采用4',6-二脒基-2-苯基吲哚（DAPI）进行复染以显示细胞核，信号呈蓝色。