Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780

immortalized patient derived kidney epithelial cell were compared to cells exposed to ER stress (thapsigargin) in the absence or present of BRD4780 treatment Patient derived kidney cells were exposed to thapsigargin in the presence and absence of BRD4780 treatment and their transcriptomic was compared

将永生化患者来源肾上皮细胞与经毒胡萝卜素（thapsigargin）诱导内质网应激（ER stress）、且分别存在或不存在BRD4780干预的细胞进行对照；同时将患者来源肾细胞分别在有、无BRD4780干预的条件下用毒胡萝卜素处理，随后对其转录组表达谱开展对比分析。