Data for Certified Foods Dyes in Over the Counter Medicines and Supplements for Children and Pregnant Women

This dataset is raw data and summary of quantified FD&C dye levels in children’s gummy vitamins, children’s tablet vitamins, prenatal vitamins, children’s cough/cold/allergy tablets & syrups, and children’s pain reliever tablets & syrups determined by high performance liquid chromatography with a photometric diode array (HPLC-DAD). The data can further be interpreted against the dosage given by each brand in each category to evaluate the consumption of the FD&C dyes and ADIs suggested for each FD&C dye by the US FDA. Syrups have the highest levels for the dosage described on the label and can be a significant contributor to FD&C dye intake for children, while all tablets and gummy vitamins showed low enough levels to be an insignificant amount of dye contributed to the ADI for most children.

本数据集包含通过高效液相色谱-光电二极管阵列检测法（high performance liquid chromatography with a photometric diode array，HPLC-DAD）定量得到的多类产品中FD&C染料（FD&C dye）含量的原始数据与汇总结果，涉及产品包括儿童软糖维生素、儿童片剂维生素、产前维生素、儿童止咳/感冒/过敏用片剂与糖浆，以及儿童止痛用片剂与糖浆。可结合各品类下各品牌标注的服用剂量对该数据进行进一步解读，以评估儿童的FD&C染料摄入量，并对照美国食品药品监督管理局（US FDA）为每种FD&C染料推荐的每日允许摄入量（Acceptable Daily Intake，ADI）开展对照分析。按照标签标注的服用剂量计算，糖浆类产品的FD&C染料含量最高，是儿童摄入FD&C染料的重要来源；而所有片剂与软糖维生素的染料含量均处于较低水平，对大多数儿童而言，其贡献的染料摄入量均未达到对应的ADI标准，无显著影响。