Impact of maternal dietary resistant starch and/or a direct high fat diet on a piglet's microbiota

Resistant starch (RS) is believed to exert beneficial effects on the gastrointestinal tract mainly due to higher levels of short chain fatty acids (SCFAs) and an improved microbiota profile. In this study, the possible maternal effect of RS was assessed. Sows were fed RS during the late gestation and lactation period and its effect on the overall health of the sow's progeny was examined. Since RS is also described to have a positive effect on metabolism, and to investigate a metabolic programming of the progeny, half of the piglets per maternal diet were assigned to a high fat diet from weaning on to 10 weeks after. The data hereby uploaded are the microbiota sequences coming from the content of the proximal colon and the RNA-seq data of liver and colon of these piglets.

抗性淀粉（Resistant Starch, RS）被认为主要通过提升短链脂肪酸（Short Chain Fatty Acids, SCFAs）水平以及优化肠道微生物群组成，对胃肠道发挥有益生理作用。本研究旨在评估抗性淀粉可能存在的母体效应：在妊娠晚期及泌乳期对母猪饲喂抗性淀粉，并探究其对仔猪整体健康状况的影响。鉴于已有研究表明抗性淀粉对代谢具有积极作用，且为探究子代的代谢程序化调控机制，本研究将每一组母体饲喂日粮对应的仔猪均分为两组，其中一组仔猪自断奶起饲喂高脂日粮，直至断奶后10周龄。本次上传的数据包含来自仔猪近端结肠内容物的微生物组测序序列，以及这些仔猪肝脏与结肠组织的RNA测序（RNA-seq）数据。