RNA sequestration in P-bodies sustains myeloid leukemia [small RNA-seq]. RNA sequestration in P-bodies sustains myeloid leukemia [small RNA-seq]

To investigate small non-coding RNA changes in AML cells following loss of P-bodies, we knocked down DDX6 in MOLM-13 cells. Overall design: Transcriptomic profiling of for small non-coding RNAs

为探究P体（P-bodies）缺失后急性髓系白血病（Acute Myeloid Leukemia, AML）细胞中小分子非编码RNA（small non-coding RNA）的表达变化，本研究在MOLM-13细胞中敲低了DEAD-box解旋酶6（DDX6）。整体实验设计：针对小分子非编码RNA的转录组分析。