Search strategies for generic justification of 18F-PSMA PET/CT in the staging of primary prostate cancer and the restaging of recurrent and metastatic prostate cancer

The dataset includes the complete, reproducible search strategies for all literature databases searched during this project. The search strategies address the following research questions:

RQ 1: In the primary staging of patients with high risk prostate cancer, what is the sensitivity, specificity and diagnostic accuracy of 18F-PSMA?

RQ 2: In patients with biochemically recurrrent prostate cancer, what is the sensitivity, specificity and diagnostic accuracy of 18F-PSMA?

RQ 3: What is the risk of adverse events (including dose) associated with receiving 18F-PSMA?

RQ 4: Is 18F-PSMA uptake associated with response to treatments for metastatic prostate cancer?

本数据集涵盖本项目中所有检索过的文献数据库的完整、可复现的检索策略。该检索策略针对以下研究问题展开：

RQ 1：高危前列腺癌患者初始分期中，氟-18标记前列腺特异性膜抗原 (18F-PSMA) 的灵敏度、特异度及诊断准确度如何？

RQ 2：生化复发性前列腺癌患者中，18F-PSMA的灵敏度、特异度及诊断准确度如何？

RQ 3：接受18F-PSMA相关操作时，所伴随的不良事件（包括辐射剂量）发生风险如何？

RQ 4：18F-PSMA摄取是否与转移性前列腺癌的治疗应答相关？