A course of medicinal plant processed buttermilk enema alters gut microbiota in obese individuals. human gut metagenome

Human gut microbiome composition contributes to food assimilation as well as low grade gut inflammation. Data suggest that specific bacterial phyla, class, or species or bacterial metabolic activities could be beneficial or detrimental to the onset of the conditions like diabetes and obesity. In the current study, 16 obese individuals received course of 15 enemas over 15 days.administered before food. Informed consent, history and physiological parameters were recorded for patients. After last enema, patients were called for follow up after 30 days.

人体肠道微生物组组成不仅参与食物消化吸收，还与低度肠道炎症密切相关。现有研究数据表明，特定的细菌门（phyla）、纲（class）、物种（species）水平菌群或细菌代谢活动，可能对糖尿病、肥胖症等疾病的发生发展产生有益或有害影响。本研究纳入16名肥胖受试者，使其在15天内完成15次灌肠疗程，所有灌肠操作均于餐前进行。研究人员记录了所有受试者的知情同意情况、病史及各项生理参数。末次灌肠结束30天后，研究人员对所有受试者完成了随访。