File S1 - Structural Insights into the Globular Tails of the Human Type V Myosins Myo5a, Myo5b, and Myo5c

Contains the following figures: Figure S1 Small Angle X-ray Scattering (SAXS) experiments with the C-terminal globular domains of human Myo5a, Myo5b, and Myo5c. Figure S2 Superpositioning of globular domains of type V myosins from yeast and humans. Figure S3 Alignment of protein sequences from the globular domains of human Myo5a, Myo5b, and Myo5c. Figure S4 Ramachandran plot of the homology model for the Myo5c globular domain. Figure S5 Mutations found in patients with Griscelli syndrome that map to the globular domain of Myo5a. Figure S6 Electrostatic potentials of Myo5a, Myo5b, and Myo5c calculated with the program Swiss PDB viewer. (PDF)

本数据集包含如下补充图：补充图S1：针对人类Myo5a、Myo5b及Myo5c的C端球状结构域开展的小角X射线散射（Small Angle X-ray Scattering, SAXS）实验；补充图S2：酵母与人类V型肌球蛋白球状结构域的叠合比对；补充图S3：人类Myo5a、Myo5b及Myo5c球状结构域的蛋白质序列比对；补充图S4：Myo5c球状结构域同源建模模型的拉马钱德兰图（Ramachandran plot）；补充图S5：格里塞利综合征（Griscelli syndrome）患者中发现的、定位至Myo5a球状结构域的突变位点；补充图S6：通过Swiss PDB Viewer软件计算得到的Myo5a、Myo5b及Myo5c的静电势分布。本数据集文件格式为PDF。