Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes

A novel and highly
practical reaction for the copper-catalyzed
intermolecular cyanotrifluoromethylation of alkenes is presented here.
This methodology provides a general and straightforward way to synthesize
a variety of useful CF3-containing nitriles, which can
be used for further preparation of pharmaceutically and agrochemically
important compounds in synthetic organic chemistry.

本文报道了一种新颖且极具实用价值的铜催化烯烃分子间氰基三氟甲基化反应。该合成方法可为多种实用的含三氟甲基（CF3）腈类化合物的合成提供通用且简便的路径，此类化合物可进一步用于有机合成化学中药物及农用化学品领域重要化合物的制备。