effect of slc11a2 deletion on placental gene expression

To investigate the function of slc11a2, we deleted slc11a2 gene in mouse placenta using cre. We performed RNA-sequencing on 14 knockout and 6 control placentas. Compare gene expression in slc11a2 knockout (KO) and the control (C) placentas.

为探究溶质载体家族11成员2（slc11a2）的功能，我们利用Cre重组酶（Cre）在小鼠胎盘中敲除了slc11a2基因。我们对14例基因敲除（knockout, KO）胎盘与6例对照胎盘开展了RNA测序（RNA-sequencing）。本研究对比了slc11a2基因敲除（KO）胎盘与对照（C）胎盘的基因表达情况。