Basic features of included literature.

Parkinson’s disease (PD) is a significant neurodegenerative disorder that affects millions of individuals worldwide and currently has limited effective treatment options. Exercise has been proposed as a non-pharmacological intervention to improve both motor and non-motor symptoms in PD. This study aims to systematically review and meta-analyze the impact of exercise interventions on sleep quality and physical functioning in PD patients. A comprehensive search of the literature up to December 15, 2023, identified randomized controlled trials that evaluated exercise interventions in PD patients. The primary outcomes were sleep quality, motor function, balance, gait performance, and quality of life. A total of 62 studies with 3,274 participants were included in the analysis. Exercise interventions led to significant improvements in sleep quality [SMD = −0.55, 95% CI (−0.91, −0.18), p = 0.003], motor capability [SMD = −0.47, 95% CI (−0.66, −0.28), p < 0.01], balance ability [SMD = 0.53, 95% CI (0.33, 0.74), p < 0.0001], gait performance [TUGT: SMD = −0.44, 95% CI (−0.60, −0.29), p = 0.0017; stride velocity: SMD = 0.38, 95% CI (0.15, 0.60), p = 0.001; step length: SMD = 0.32, 95% CI (0.10, 0.54), p = 0.004], and quality of life [SMD = −0.38, 95% CI (−0.73, −0.03), p = 0.04] (p < 0.05). Exercise is an effective intervention for enhancing sleep quality and improving physical function in PD patients. These findings underscore the importance of incorporating exercise into the management strategies for PD.

帕金森病（Parkinson’s disease, PD）是一种累及全球数百万人群的重要神经退行性疾病，目前临床有效治疗手段十分有限。运动作为一种非药物干预手段，被提议用于改善帕金森病患者的运动与非运动症状。本研究旨在对运动干预针对帕金森病患者睡眠质量及躯体功能的影响开展系统综述与荟萃分析。我们于2023年12月15日前全面检索相关文献，共纳入评估帕金森病患者运动干预效果的随机对照试验。本研究的主要结局指标包括睡眠质量、运动功能、平衡能力、步态表现及生活质量。最终共有62项研究、合计3274名受试者被纳入本次分析。运动干预可显著改善帕金森病患者的下述指标：睡眠质量[标准化均数差（Standardized Mean Difference, SMD）=−0.55，95%置信区间（Confidence Interval, CI）=(−0.91, −0.18)，p=0.003]、运动能力[SMD=−0.47，95%CI=(−0.66, −0.28)，p<0.01]、平衡能力[SMD=0.53，95%CI=(0.33, 0.74)，p<0.0001]、步态表现[计时起立行走测试（Timed Up and Go Test, TUGT）：SMD=−0.44，95%CI=(−0.60, −0.29)，p=0.0017；步速：SMD=0.38，95%CI=(0.15, 0.60)，p=0.001；步长：SMD=0.32，95%CI=(0.10, 0.54)，p=0.004]以及生活质量[SMD=−0.38，95%CI=(−0.73, −0.03)，p=0.04]（所有指标p<0.05）。运动干预是提升帕金森病患者睡眠质量、改善其躯体功能的有效手段。本研究结果凸显了将运动纳入帕金森病管理策略的重要意义。