RNAseq of canine marginal zone lymphoma (MZL) and follicular lymphoma (FL)

Canine indolent B-cell lymphomas (CIBCL) are a heterogeneous group of malignancies arising from neoplastic transformation of mature B-lymphocytes. Two WHO histotypes of CIBCL are more frequent: marginal zone lymphoma (MZL) and follicular lymphoma (FL).Herein 12 CIBCL, morphologically classified as FL (n=7) and MZL (n=5), were analyzed by means of RNA-seq.

犬类惰性B细胞淋巴瘤（Canine indolent B-cell lymphomas, CIBCL）是一类起源于成熟B淋巴细胞肿瘤性转化的异质性恶性肿瘤群体。该类淋巴瘤中，两种最为常见的世界卫生组织（World Health Organization, WHO）组织学亚型为边缘区淋巴瘤（MZL）与滤泡性淋巴瘤（FL）。本研究纳入12例CIBCL，经形态学分类为滤泡性淋巴瘤（FL，n=7）与边缘区淋巴瘤（MZL，n=5），并通过RNA测序（RNA-seq）完成了相关分析。