MOESM2 of Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

Additional file 10. Function of genes associated with common differentially regulated pathways during replicative and pre-mature senescence induction. Function of each of the genes associated with the commonly differentially regulated pathways (up- and down-regulated) on replicative and 20 Gy irradiation induced senescence in the MRC-5 fibroblasts and HFF strains. Blue color denotes that previous studies have functionally associated these genes with induction of senescence.

附加文件10：复制性衰老（replicative senescence）与过早衰老（pre-mature senescence）诱导过程中，与共有差异调控通路（common differentially regulated pathways）相关的基因功能。本数据集收录了在MRC-5成纤维细胞与HFF细胞株中，与复制性衰老及20 Gy辐射诱导衰老相关的共有差异调控（上调与下调）通路内各基因的功能。其中蓝色标记代表此前已有研究将这些基因与衰老诱导过程建立了功能关联。