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Treatment for unicompartmental knee osteoarthritis is controversial in young patients with concomitant anterior cruciate ligament (ACL) deficiency. The aim of the current study is to report long-term results after the combination of unicompartmental knee arthroplasty (UKA) and ACL reconstruction. Retrospective study of one-stage medial UKA and ACL reconstruction performed on 8 patients at a mean age of 52 years (42 to 60). Clinical and radiological results were assessed and analyzed after a mean follow-up of 14.6 years. A control cohort of 8 patients with intact ACL, treated by UKA in isolation, was selected for a comparative study. Patients were very satisfied and mean personal satisfaction rate was 8.8 (4 to 10). At the last follow-up, mean WOMAC score was 26 (1 to 52) and mean global KSS was 154 (102 to 200). No statistically significant differences were found between groups. One revision surgery to total knee arthroplasty was performed 9 years after the combined procedure due to aseptic loosening. One more case of clinical deterioration was observed.<br>Satisfactory mid-term results are achieved with the combined UKA and ACL reconstruction, which represents a good alternative to preserve bone stock and functional level of the knee in young patients. However, clinical deterioration can be observed in the long-term follow-up.

针对合并前交叉韧带（anterior cruciate ligament, ACL）缺损的年轻患者，单间室膝关节骨关节炎（unicompartmental knee osteoarthritis）的治疗方案尚存争议。本研究旨在报道单间室膝关节置换术（unicompartmental knee arthroplasty, UKA）联合前交叉韧带重建术后的长期随访结果。
本研究为回顾性研究，纳入8例平均年龄为52岁（42~60岁）的患者，行一期内侧单间室膝关节置换术联合前交叉韧带重建术。对平均随访14.6年后的临床及影像学结果进行评估与分析。另选取8例ACL完整、仅接受单间室膝关节置换术治疗的患者作为对照队列，开展对比研究。
患者总体满意度极高，平均个人满意度评分为8.8分（4~10分）。末次随访时，平均WOMAC评分（WOMAC score）为26分（1~52分），平均总体膝关节学会评分（Knee Society Score, KSS）为154分（102~200分）。两组间未发现具有统计学意义的差异。1例联合术后9年因无菌性松动接受全膝关节置换术翻修，另有1例患者出现临床病情恶化。
单间室膝关节置换术联合前交叉韧带重建术可获得满意的中期疗效，是年轻患者保留骨量与膝关节功能水平的良好替代方案。但在长期随访中仍可观察到临床病情恶化的情况。