Supporting data for 'Thermodynamic origins of two-component multiphase condensates of proteins' (2023)

This file is part of the supporting data for the manuscript 'Thermodynamic origins of two-component multiphase condensates of proteins', and contains the data used to plot the figures and the full sequence populations from the four main genetic-algorithm runs presented in the main text. An example LAMMPS input script (with pair parameters for the Mpipi coarse-grained model) used in this work and an example input configuration for a multilayered system that can be used as the initial system in a coevolution run, as well as a multilayered system containing the WT A1 LCD in the centre and its predicted partner protein are also included. <br> The structure and contents of this file are outlined in the README file in the root directory.

本文件为论文《蛋白质双组分多相凝聚体的热力学起源》配套支撑数据的组成部分，包含用于绘制正文中展示的图表所需的数据，以及正文中展示的四项主要遗传算法（genetic algorithm）运行所得的完整序列种群结果。此外，本数据集还涵盖本研究中使用的示例LAMMPS输入脚本（内置Mpipi粗粒度模型的成对相互作用参数）、可作为共进化运行初始系统的多层系统示例输入配置，以及中心包含野生型A1 LCD（WT A1 LCD）及其预测互作蛋白的多层系统。本文件的结构与内容详见根目录下的README文件。