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Human Protein Atlas - Tissue

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v24.proteinatlas.org2025-01-09 收录
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https://v24.proteinatlas.org/humanproteome/tissue
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资源简介:
This resource of the Human Protein Atlas focuses on the expression profiles in human tissues of genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using conventional and multiplex immunohistochemistry. All underlying images of immunohistochemistry stained normal tissues are available together with knowledge-based annotation of protein expression levels. The protein data covers 15302 genes (76%) for which there are available antibodies. The mRNA expression data is derived from deep sequencing of RNA (RNA-seq) from 40 different normal tissue types. More information about the specific content and the generation and analysis of the data in the resource can be found on the Methods Summary. Learn about: protein localization in tissues at a single-cell level if a gene is enriched in a particular tissue (specificity) which genes have a similar expression profile across tissues (expression cluster)

本资源聚焦于人类蛋白质图谱中人类组织中基因在mRNA和蛋白质水平上的表达谱。来自44种正常人类组织类型的蛋白质表达数据,是通过使用传统和多重免疫组化技术的基于抗体的蛋白质分析获得的。所有免疫组化染色的正常组织图像以及蛋白质表达水平的知识库注释均一并提供。蛋白质数据涵盖了15302个基因(占总数的76%),对于这些基因均有可用的抗体。mRNA表达数据来源于40种不同正常组织类型的RNA(RNA-seq)深度测序。关于资源中特定内容的详细信息和数据的生成与分析方法,可查阅方法概要。了解以下内容: - 在组织中的单细胞水平上的蛋白质定位 - 基因在特定组织中的富集情况(特异性) - 在不同组织中具有相似表达谱的基因(表达簇)
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