Efsa'S Compendium Of Botanicals
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EFSA’s Compendium of Botanicals is a database of botanicals that are reported to contain naturally occurring substances of possible concern for human health when present in food. The compendium is not intended to conclude on the safety or non-safety of the listed botanical species but to help with the safety assessment of botanicals and botanical preparations intended for use in food, including supplements, by facilitating hazard identification. The compendium does not list all bioactive substances present in a given botanical and their potential health effects, nor does it flag botanicals or botanical substances of possible concern for animal health when used as feed or feed additives. However, where adverse effects reported on animal health were found in the literature, they are reported in the compendium. Information provided by the Compendium: The <strong>Botanical Species</strong>. The taxonomy database “the Plant List” was taken as a reference. If not found in this database, or where the scientific name of the botanical was not officially accepted (“unresolved”), ARSGRIN was used. If still unsuccessful, the International Plant Name Index was consulted. The <strong>Family</strong>. In many cases, botanicals from a given family contain similar groups of compounds. Therefore, knowing the family name may provide indications of the possible presence of similar compounds in other species not included in the compendium. The Plant List database was used as the main source of information. The<strong> Plant Part</strong> in which the compounds of concern were reported to be present, or for which adverse effect(s) was reported without any identification of substances of concern. The <strong>Preparation, </strong>including essential oils, linked to the presence of a substance of possible concern or an adverse effect. The <strong>Substances or chemical groups of concern</strong> when they were identified. This compendium is intended for hazard identification, whereas risk assessment would require additional information on the concentration of the substance of possible concern in the product on the market, as well as the level of exposure of the consumer to this substance. The <strong>Effect Description</strong> found in the scientific literature when they could not be associated to any of the compound(s) of concern. The toxicity of the compound(s) of concern will be characterized in a next phase of development of the compendium. The <strong>Reference</strong> retrieved from literature searches for the data given, and/or standard reference text books providing monographs or more general scientific information for the botanicals considered.
欧洲食品安全局(European Food Safety Authority,EFSA)的植物纲要汇编(Compendium of Botanicals)是一个收录了据报道在食品中存在时可能引发人类健康关切的天然物质的植物类数据库。 本汇编并非旨在判定所列植物物种的安全性或非安全性,而是通过助力危害识别,为食品(包括膳食补充剂)中使用的植物及其制剂的安全性评估提供支持。 本汇编并未穷尽某一特定植物中存在的所有生物活性物质及其潜在健康效应,也未标注用作饲料或饲料添加剂时可能引发动物健康关切的植物或植物成分。不过,若文献中存在关于其对动物健康产生不良影响的报道,则会在汇编中予以收录。 汇编提供的信息包括: **植物物种(Botanical Species)**:以分类学数据库《植物名录》(The Plant List)为参考依据。若该数据库未收录该物种,或该植物的学名未被官方认可(“未决分类”),则采用ARSGRIN数据库;若仍未查询到结果,则参考国际植物名称索引(International Plant Name Index)。 **科(Family)**:多数情况下,同一科的植物含有同类别的化合物,因此知晓植物科属可辅助推断汇编未收录的其他物种中可能存在的同类化合物。本部分信息主要来源于《植物名录》(The Plant List)数据库。 **植物部位(Plant Part)**:据报道存在目标关切物质,或虽未识别出具体关切物质但存在不良效应的植物部位。 **制剂(Preparation)**:与目标关切物质或不良效应相关的制剂类型,包括精油。 **关切物质或化学类别(Substances or chemical groups of concern)**:在可识别的情况下收录的相关物质。本汇编仅用于危害识别,风险评估则需额外获取市场在售产品中目标关切物质的浓度,以及消费者对该物质的暴露水平等信息。 **效应描述(Effect Description)**:在科学文献中发现的、无法与任何特定关切物质相关联的不良效应。针对关切物质的毒性表征工作将在本汇编后续开发阶段开展。 **参考文献(Reference)**:检索文献获取上述数据的来源,以及为所涉植物提供专论或更通用科学信息的标准参考教科书。



