A rheumatoid factor specific mimotope identified by a peptide display library.

The epitope-specific IgM rheumatoid factor bound IgG and an anti-idiotype that recognized a light chain determinant on the serum rheumatoid factor of approximately 80% of seropositive individuals with rheumatoid arthritis.

表位特异性IgM型类风湿因子（rheumatoid factor, RF）可结合免疫球蛋白G（immunoglobulin G, IgG）以及一种抗独特型抗体，该抗独特型可识别约80%类风湿关节炎（rheumatoid arthritis, RA）血清学阳性个体血清中类风湿因子的轻链决定簇。