Non-invasive Prenatal Testing Study: Comparison England, France, Germany, 2021-2022

This project proposed a new approach to explore ethical issues arising from the clinical implementation of genomics in antenatal care in the twenty first century. Situated at the interface between sociology, bioethics and law/social policy this research seeks to gain in-depth understanding of the situations in which these questions emerge and are experienced by the key-stakeholders (health professionals, patients, scientists, policy-makers), and provide insight into the underlying value systems which promote them. This comparative investigation takes non-invasive prenatal testing (NIPT) in England, France and Germany as a case study. NIPT is a rapidly developing genomic technology that is constantly widening its scope and opening up new possibilities in reproductive medicine. These data are part of a wider comparative study combining a literature review and an empirical research (semi-structured interviews with different stakeholders, including pregnant women/couples and health professionals) to explore the ethical issues arising from prenatal genetics and genomics in England, France and Germany.

本项目提出了一种新方法，旨在探讨21世纪基因组学在产前保健临床应用中引发的伦理问题。本研究处于社会学、生物伦理学与法律/社会政策的交叉领域，旨在深入理解这些伦理问题出现的情境及其被关键利益相关者（卫生专业人员、患者、科学家、政策制定者）所体验的过程，并洞察推动这些问题产生的潜在价值体系。这项比较研究以英国、法国和德国的无创产前检测（NIPT）为案例。无创产前检测（NIPT）是一项快速发展的基因组学技术，其应用范围不断扩大，为生殖医学开辟了新的可能性。这些数据是一项更广泛的比较研究的一部分，该研究结合了文献综述和实证研究（对不同利益相关者的半结构化访谈，包括孕妇/夫妇和卫生专业人员），旨在探讨英国、法国和德国产前遗传学与基因组学引发的伦理问题。