Co-expression Analysis Reveals Dysregulated miRNAs and miRNA-mRNA Interactions in the Development of Contrast-induced Acute Kidney Injury [mRNA]

Conclusions:In conclusion, our present study contributes to the first evidence of miRNA-mRNA regulations in the development of kidney injury following an intra-arterial contrast injection route. These novel findings provide insights into the underlying mechanisms of CI-AKI.结论：综上所述，本研究首次提供了动脉内造影剂注射途径所致肾损伤发生过程中微小核糖核酸-信使核糖核酸（miRNA-mRNA）调控关系的相关证据。上述创新性发现为阐释造影剂相关急性肾损伤（Contrast-Induced Acute Kidney Injury, CI-AKI）的潜在发病机制提供了全新研究视角。