Survival and gross pathology of mice passively treated with mAbs.

ap value vs. controls determined from Kaplan-Meier survival plots by log-rank (Mantel-Cox) test, bold values are statistically significant (pbpositive spleen cfu was determined on survivors and assumed to occur in mice that died before study endpoint.cp values vs. controls determined by Fisher's exact test, bold values are statistically significant (pdspleen cfu was assessed on survivors only; values indicate cfu determined by plating 100 µl from a 1 ml spleen homogenate; T indicates too numerous to count.edetermination of abscess formation on internal organs was performed on survivors only.

a. 基于Kaplan-Meier生存曲线（Kaplan-Meier survival plots），通过对数秩（Mantel-Cox）检验（log-rank (Mantel-Cox) test）计算ap值以与对照组比较，加粗数值表示具有统计学显著性（p；b. 脾脏菌落形成单位（CFU, Colony-Forming Unit）阳性结果仅在存活小鼠中检测得到，研究终点前死亡的小鼠脾脏CFU状态按阳性推定；c. 基于Fisher精确检验（Fisher's exact test）计算cp值以与对照组比较，加粗数值表示具有统计学显著性（p；d. 脾脏CFU仅对存活小鼠进行检测；数值代表通过涂布100μL取自1mL脾脏匀浆的样本所得的CFU计数；标注‘T’表示菌落过多无法计数；e. 内脏器官脓肿形成情况的检测仅针对存活小鼠开展。