OrthoMaM

Molecular data play a key role in phylogenetic and molecular evolution inferences. Mammalian genomics and systematics provides us with a clear example, with several open evolutionary questions now able to be answered. However, molecular studies have until present used only a handful of standard markers and have not attempted to utilise the information contained within the increasingly large pool of mammalian genome sequences. The identification and utilisation of potentially new informative markers from this comparative genomics pool can help to further resolve the mammalian phylogenetic tree, and better understand the evolutionary dynamics of genes.分子数据在系统发育与分子演化推断中发挥着关键作用。哺乳动物基因组学与系统分类学便是绝佳例证，诸多此前悬而未决的演化难题如今已可得到解答。然而迄今为止，分子生物学研究仅采用了少量标准分子标记，尚未尝试利用规模日益庞大的哺乳动物基因组序列库中蕴含的信息。从该比较基因组学库中识别并利用潜在的新型信息性分子标记，将有助于进一步完善哺乳动物系统发育树的解析，并加深对基因演化动力学的理解。

搜集汇总

背景与挑战

背景概述

OrthoMaM数据集专注于利用分子数据来推断哺乳动物的系统发育和进化过程。它旨在通过识别和利用比较基因组学中的新信息标记，以解决现有研究仅依赖少数标准标记的局限性，从而更精确地解析哺乳动物进化树并探究基因进化动态。