椎骨/石蜡包埋组织切片(CSTR:17621.07.B0116.9871.2013.H2.1)

省千佛山医院病理科是我省病理质量控制中心，具有完善的病理标本标准化入库流程、技术规范和质量控制体系，并实现院内资源信息共享。2003年即创立了我省第一家新鲜标本组织库；培养了一批熟练掌握组织样本采集、保存技能的人才；并根据不同分子亚型对肺癌、肝癌、乳腺癌、结直肠癌等疾病开展了前沿研究；在精准医学、慢病、生物技术应用等方面，充分利用人类遗传资源，自2011年后，承担本院涉及人类遗传资源的项目合计454项。其综合性肿瘤遗传资源来自医院各临床科室对患者进行手术或其他途径如内镜活检、针吸活检、脱落细胞涂片等获取的样本，所包含的生物样本有良恶性肿瘤、癌前病变以及与肿瘤发生相关的感染性病变组织、细胞和体液等，经病理科进行专业的标本取材、组织和细胞处理、石蜡包埋、染色等获得的新鲜组织（部分血液）、石蜡组织、组织切片和细胞涂片等，同时获取相应患者临床信息（包括：性别，年龄，病变部位，病变大小，浸润情况，有无淋巴结转移及其病理分级和分期，随访等）。部分肿瘤患者如非小细胞肺癌，结直肠癌，乳腺癌，胃癌、甲状腺癌、子宫内膜癌、肝癌和卵巢癌等进行分子病理检测，获得其基因突变、融合、甲基化等信息；部分特殊病例将其切片扫描为数字切片进行人工智能诊断技术的开发，在肿瘤生物样本库的采集、存储和利用方面独树一帜，发挥了省内领头羊的作用。（性别；女性；国别：中国；民族：资料不详；籍贯：不详；出生年份：-；生命周期：年轻老年人（60-74岁）；妊娠期：未填写；健康状况：肿瘤）

The Department of Pathology of Shandong Provincial Qianfoshan Hospital serves as the provincial pathology quality control center, with a complete standardized workflow for pathological specimen intake, technical specifications, and a quality control system, and has realized intra-hospital sharing of resource information. In 2003, it established the first fresh specimen tissue bank in the province. The department has trained a cohort of professionals proficient in tissue sample collection and preservation, and carried out cutting-edge research on diseases including lung cancer, liver cancer, breast cancer, and colorectal cancer based on their distinct molecular subtypes. Leveraging human genetic resources in the fields of precision medicine, chronic diseases, and biotechnological applications, it has undertaken a total of 454 projects involving human genetic resources in the hospital since 2011. Its comprehensive tumor genetic resources are derived from samples obtained from patients by the hospital's various clinical departments via surgery or other approaches including endoscopic biopsy, fine-needle aspiration biopsy, and exfoliative cytology smears. The included biological samples cover benign and malignant tumors, precancerous lesions, infectious lesion tissues, cells, and body fluids associated with tumorigenesis. These samples undergo professional processing by the Department of Pathology, including specimen harvesting, tissue and cell handling, paraffin embedding, and staining, yielding fresh tissues (partial blood samples), paraffin-embedded tissues, tissue sections, and cell smears. Corresponding clinical information of the patients is also collected, including gender, age, lesion location, lesion size, invasion status, presence or absence of lymph node metastasis, pathological grading and staging, and follow-up records. For some tumor patients, including those with non-small cell lung cancer, colorectal cancer, breast cancer, gastric cancer, thyroid cancer, endometrial cancer, liver cancer, and ovarian cancer, molecular pathological testing is performed to obtain information such as gene mutations, gene fusions, and methylation profiles. For certain special cases, their slides are scanned into digital slides for the development of artificial intelligence diagnostic technologies. The department has a distinctive position in the collection, storage, and utilization of tumor biobanks, serving as a leading institution in the province. (Demographic information: Gender: Female; Country: China; Ethnicity: Unknown; Place of Origin: Unknown; Year of Birth: N/A; Life Cycle: Young-old Adults (60–74 Years Old); Pregnancy Status: Unfilled; Health Status: Tumor)