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Genome-scale CRISPR-Cas9 knockout screens for enterovirus D68 and rhinovirus C15

ChEBI2019-07-10 更新2026-07-12 收录

病毒宿主因子筛选

CRISPRi功能基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8125 数据链接链接失效反馈

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资源简介：

Genome-scale CRISPR-Cas9 knockout screens for enterovirus D68 and rhinovirus C15

应用场景：

创建时间：

2019-07-10

抗体药物研发

CRISPRi功能基因组学

Following nearly five decades with few approved therapies for acute myeloid leukemia (AML), the last three years have brought stellar progress with the U.S. Food and Drug Administration approving a nu

NIAID Data Ecosystem50

Additional file 1 of CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens

CRISPRi功能基因组学

基因必要性筛选

Additional File 1: Table S1. All compared sets of core-fitness and common-essential genes with annotations.

Figshare2021-11-17 更新50

Differential gene expression (FDR 0.05) for CRISPR edited clones.

CRISPRi功能基因组学

免疫应答分析

hTLR4 Cells were transfected a CRISPR/Cas9 construct and a gRNA specific for the rs17622517 locus. Wild type, heterozygous or homozygous clones were isolated and then treated with no LPS, LPS for 90 m

Figshare2021-07-27 更新10

BT20_24hr_DMSOvERLOTINIB_RNAseq and WHOLE GENOME CRISPR screen

癌症药物机制研究

CRISPRi功能基因组学

BT20 (TNBC) cells were cultured with either DMSO (v/v%) or Erlotinib (10uM) for 24 hours to observe differential expression changes between conditions. CAS-9 expressing BT20 (TNBC) cells were transduc

NIAID Data Ecosystem50

List of guideRNAs used for validation.

病毒宿主因子筛选

CRISPR功能分析

While SARS-CoV-2 primarily infects the respiratory tract, clinical evidence indicates that cells from diverse cell types and organs are also susceptible to infection. Using the CRISPR activation (CRIS

Figshare2025-07-17 更新20

Genome-scale CRISPR-Cas9 knockout screens for enterovirus D68 and rhinovirus C15

资源简介：

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