Identification of STAT5 target genes in human CB HSC, CMP, GMP and MEP
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Identification of STAT5 target genes in human CB HSC, CMP, GMP and MEP
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2011-01-22
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Additional file 6 of Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis
Additional file 6: Supplemental file 2. The gene regulatory network with threshold of 3
Figshare2020-12-30 更新60
Comparative gene expression of CD34+ human hematopoietic progenitor cells upon knockdown of STAT5. Homo sapiens
The objective of the study is to identify the genes regulated by STAT5 in very primitive human hematopoietic stem progenitor cells (HSPCs). We used Affymetrix Human Genome U133 Plus 2.0 microarrays to
NIAID Data Ecosystem50
Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework [RNAseq_THP1_GSK-LSD1]. Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework [RNAseq_THP1_GSK-LSD1]
Genome-wide transcription factor binding profiles provide valuable insights into hematopoietic development and malignancies. Today, advanced computational methods exploit cis-regulatory information to
NIAID Data Ecosystem30
Defining STAT5 target genes in thymic precursor cells at pre- and post-commitment stages. Defining STAT5 target genes in thymic precursor cells at pre- and post-commitment stages
STAT5 is critical for inducing lineage specifying transcription factors, establishing effector gene programs, upregulating IL-2Rα (also known as CD25), and supporting cell survival in response to envi
NIAID Data Ecosystem50
Myb is regulated by -81 enhancer eRNA transcript Myrlin through recruitment of MLL1 complex. Myb is regulated by -81 enhancer eRNA transcript Myrlin through recruitment of MLL1 complex
The Myb proto-oncogene encodes the transcription factor c-MYB, which is critical for the proliferation and differentiation of hematopoietic stem and progenitor cells. Distant enhancers of Myb expressi
NIAID Data Ecosystem40
