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Supporting data for "Comprehensive toxicological evaluation of novel anti-hypertensive small molecule KSD179019".

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DataCite Commons2022-09-07 更新2025-04-16 收录
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https://datahub.hku.hk/articles/dataset/Supporting_data_for_Comprehensive_toxicological_evaluation_of_novel_anti-hypertensive_small_molecule_KSD179019_/20477931/1
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资源简介:
The data are results obtained from the in-vitro and in-vivo toxicological studies conducted for the safety evaluation of novel anti-hypertensive small molecule KSD179019. The in-vitro study includes MTT and Ames test to evaluate weather the drug is carcinogenic to cells and bacteria. Further, the in-vivo data is from acute, sub-chronic and chronic toxicity study to identify the maximum tolerable dose levels without causing any toxic effect. <br> The data set contains Images of animals necropsy, haematology and histology. raw data obtained from the spectophotometer after performing the biochemical assays. prism graphpad files obtrained after interpreting the results .

这些数据是为新型抗高血压小分子KSD179019的安全性评价而开展的体外(in-vitro)和体内(in-vivo)毒理学研究结果。体外研究包括MTT试验和Ames试验,旨在评估该药物是否对细胞和细菌具有致癌性。此外,体内数据来自急性、亚慢性和慢性毒性研究,用于确定无任何毒性效应的最大耐受剂量水平。<br>该数据集包含动物尸检、血液学和组织学图像,以及生化测定后从分光光度计获得的原始数据,还有结果解读后生成的GraphPad Prism文件。
提供机构:
HKU Data Repository
创建时间:
2022-09-07
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