Characterization of the Oropharyngeal Microbiomes in COVID-19 Omicron Variety Infection and Recovery Patients. human oral metagenome

To characterize the oropharyngeal microbiota in patients with SARS-CoV-2 Omicron variety and recovered patients; evaluate the potential of microbiome as non-invasive biomarkers for Omicron variety. Exploration of oropharyngeal microbiomes between different strains.We collected oropharyngeal swabs from 297 confirmed cases of COVID-19 Omicron variant (CCO), 222 confirmed case of Omicron who recovered (CCOR), 73 confirmed cases of original strain (CCOS) and 199 healthy controls (HC), then completed Miseq sequencing.

本研究旨在解析新型冠状病毒（SARS-CoV-2）奥密克戎变异株感染患者及康复患者的口咽部微生物群特征，评估微生物组作为奥密克戎变异株感染非侵入性生物标志物的应用潜力，并探究不同毒株感染人群口咽部微生物组的差异。本研究共收集297例新型冠状病毒肺炎奥密克戎变异株确诊患者（CCO）、222例奥密克戎变异株确诊康复患者（CCOR）、73例原始毒株确诊患者（CCOS）及199名健康对照者（HC）的口咽拭子样本，并完成MiSeq测序。