Harnessing Repetition-Rate-Dependent Microbubble Chains for Precision Microflow Control in Laser-Induced Microfluidic Chips: Original Experimental Data and Analysis

This dataset comprehensively supports the findings of the research article entitled "Harnessing Repetition-Rate-Dependent Microbubble Chains for Precision Microflow Control in Laser-Induced Microfluidic Chips." The study introduces a novel, programmable microflow control technique utilizing the collective dynamics of femtosecond laser-induced microbubble (FLIMB) chains, governed solely by the laser repetition rate. Research Background and Significance:Precise flow control at the microscale without mechanical components remains a significant challenge in microfluidics. This work demonstrates that the rising velocity of FLIMB chains follows a robust logarithmic scaling law with respect to the laser repetition rate (1-1000 Hz). It identifies two distinct, reconfigurable flow regimes: a microbubble "annihilation" mode at low rates (Data Content and Structure: The dataset contains original experimental measurements, processed data, and fitting parameters necessary to reproduce the figures and conclusions of the associated study. Key components include: Raw and processed data​ for microbubble diameter, rising velocity, and count across different laser repetition rates and liquid media (water, ethanol, methanol). Fitting parameters​ for the logarithmic relationship (v = a ln(f + c) + b) between velocity (v) and repetition rate (f), including uncertainties and coefficients of determination (R²). High-resolution image data​ used for quantitative analysis via particle tracking and image processing. Experimental Methodology: Data were generated using a Ti:Sapphire femtosecond laser amplifier (800 nm center wavelength, 50 fs pulse width). The laser was focused into a quartz cuvette containing the liquid samples. Microbubble behavior was recorded with a digital camera (Nikon D700). The dataset reflects systematic variation of key parameters: Laser Repetition Rate:​ 1 - 1000 Hz Pulse Energy:​ 22.5 μJ, 213 μJ, 2187 μJ Liquid Media:​ Distilled water, ethanol, methanol (purity ≥ 99.5%) Data File Organization and Usage: The dataset is organized into clear categories for ease of reuse. The file README.txtprovides a detailed guide to the dataset's structure, file naming conventions, and column definitions for all tabular data (e.g., .csvfiles). This facilitates replication of the analysis, secondary research, and integration into computational models. The file Figures.pdfcontains the assembled result figures corresponding to those in the main text. Reusability and Value: This dataset adheres to the FAIR (Findable, Accessible, Interoperable, Reusable) principles. It provides a complete record of the experimental results, enabling: Independent verification​ of the reported logarithmic scaling law and flow regimes. Further analysis​ and modeling of laser-induced microbubble dynamics. Benchmarking​ for future studies in optofluidics and active microflow control. Design parameters​ for developing microfluidic devices utilizing this optical control mechanism. By providing both raw and analyzed data, this dataset serves as a valuable resource for researchers in microfluidics, laser-material interactions, and lab-on-a-chip technology.

本数据集全面支撑了题为《利用依赖重复率的微气泡链实现激光诱导微流控芯片中的精准微流控制》的研究论文的核心结论。该研究提出了一种全新的可编程微流控制技术，该技术利用飞秒激光诱导微气泡（femtosecond laser-induced microbubble, FLIMB）链的集体动力学行为，且仅由激光重复率调控。

研究背景与意义：无需机械组件的微尺度精准流控仍是微流控领域的重大挑战。本研究表明，FLIMB链的上升速度与激光重复率（1~1000 Hz）遵循稳健的对数标度律。研究还识别出两种截然不同、可重构的流控模式：低重复率下的微气泡“湮灭”模式。

数据集内容与结构：本数据集包含复现本研究的图表与结论所需的原始实验测量数据、处理后数据以及拟合参数。核心组成部分包括：不同激光重复率与液体介质（水、乙醇、甲醇）下的微气泡直径、上升速度及数量的原始与处理后数据；速度（v）与重复率（f）之间对数关系（v = a ln(f + c) + b）的拟合参数，包含不确定度与决定系数（R²）；用于通过粒子追踪与图像处理开展定量分析的高分辨率图像数据。

实验方法：数据通过钛蓝宝石飞秒激光放大器（中心波长800 nm，脉冲宽度50 fs）采集得到。该激光被聚焦于装有液体样品的石英比色皿中。微气泡的行为通过数码相机（尼康D700）记录。本数据集反映了关键参数的系统变化：激光重复率：1~1000 Hz；脉冲能量：22.5 μJ、213 μJ、2187 μJ；液体介质：蒸馏水、乙醇、甲醇（纯度≥99.5%）。

数据文件组织与使用说明：本数据集按清晰类别组织，便于复用。README.txt文件详细说明了数据集的结构、文件命名规范，以及所有表格数据（如.csv文件）的列定义，可辅助分析复现、二次研究以及集成至计算模型中。Figures.pdf文件包含与正文图表对应的组装结果图。

复用性与价值：本数据集遵循FAIR（可发现、可访问、可互操作、可复用）原则。其完整记录了所有实验结果，可支撑以下应用：独立验证已报道的对数标度律与流控模式；对激光诱导微气泡动力学开展进一步分析与建模；为光流控与主动微流控领域的未来研究提供基准测试数据；为利用该光学控制机制开发微流控器件提供设计参数。通过同时提供原始数据与分析后数据，本数据集可为微流控、激光-材料相互作用以及芯片实验室技术领域的研究人员提供宝贵的研究资源。