Crystal Structure of the Catalytic Domain of Factor XI in complex with (R)-1-(4-(4-(hydroxymethyl)-1,3,2-dioxaborolan-2-yl)phenethyl)guanidine

Crystal Structure of the Catalytic Domain of Factor XI in complex with (R)-1-(4-(4-(hydroxymethyl)-1,3,2-dioxaborolan-2-yl)phenethyl)guanidine Descriptor: (R)-1-(4-(4-(HYDROXYMETHYL)-1,3,2-DIOXABOROLAN-2-YL)PHENETHYL)GUANIDINE, BICARBONATE ION, Coagulation factor XI, ... Authors: Lazarova, T.I, Jin, L, Rynkiewicz, M.J, Gorga, J.C, Bibbins, F, Meyers, H.V, Babine, R.E, Strickler, J.E. Deposit date: 2005-05-10 Release date: 2006-05-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa. Bioorg.Med.Chem.Lett., 16, 2006

凝血因子XI催化结构域与(R)-1-(4-(4-(羟甲基)-1,3,2-二氧杂硼戊环-2-基)苯乙基)胍复合物的晶体结构
描述：(R)-1-(4-(4-(羟甲基)-1,3,2-二氧杂硼戊环-2-基)苯乙基)胍、碳酸氢根离子、凝血因子XI（Coagulation factor XI）等
作者：Lazarova, T.I、Jin, L、Rynkiewicz, M.J、Gorga, J.C、Bibbins, F、Meyers, H.V、Babine, R.E、Strickler, J.E
提交日期：2005-05-10
发布日期：2006-05-09
最后修改日期：2024-10-16
研究方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.25埃（Å）
引用：芳基硼酸类XIa因子潜在抑制剂的合成及体外生物学评价，《Bioorg.Med.Chem.Lett.》，2006年，第16卷