DNA methylation of mortal and immortal breast cells

DNA methylation changes during immortalization of breast cells. The aim of the study was to determine whether differential epigentic state of TERT gene is involved in immortalization of breast cells. comparison of Pre-Stasis, Post-Selection, and immortal cells

乳腺细胞永生化过程中的DNA甲基化（DNA methylation）变化。本研究旨在明确TERT基因（telomerase reverse transcriptase gene）的差异表观遗传状态是否参与乳腺细胞的永生化进程。本研究对停滞前期（Pre-Stasis）、筛选后（Post-Selection）细胞及永生化细胞进行了比较分析。