Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide

Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... Authors: Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. Deposit date: 2012-02-24 Release date: 2012-05-23 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012

瘟病毒属（Pestivirus）BVDV-1（牛病毒性腹泻病毒1型）来源的E(rns)糖蛋白活性位点突变体与CpUpC三核苷酸复合物的晶体结构
相关组分：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose）、E(rns)糖蛋白……
作者：Krey T、Bontems F、Vonrhein C、Vaney M.-C、Bricogne G、Ruemenapf T、Rey F.A.
提交日期：2012-02-24
发布日期：2012-05-23
最后修改日期：2024-10-30
实验方法：X射线衍射（分辨率3.01埃）
引用文献：《瘟病毒包膜糖蛋白E(rns)的晶体结构及其核糖核酸酶活性机制分析》（Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity），发表于《Structure》，20卷，2012年