A system for treatment of diabetic foot ulcers using led irradiation and natural latex

Abstract Introduction: We developed and tested a new system for inducing the healing of diabetic foot ulcers. The system relies on the regenerative properties of its two components: an insole with a sheet of natural latex and a device that contains a matrix of light emitting diodes with wavelength of 635 nm. Methods The electronic and latex based devices were developed, and a four weeks test was performed in one control group (CG) of five ulcers and one experimental group (EG) of eight ulcers. The CG was treated with a standard approach, based on a silver-releasing foam dressing, and the EG was treated with the system under test. For each ulcer, an index for quantifying the percentage ulcer recovery, named CRU(%), has been calculated; a CRU(%) = 0% means no healing, and a CRU(%) = 100% means total healing. Results There were statistically significant increases of CRU(%) of 51.8% (p = 0.022), for the CG, and of 78.4% (p

摘要与引言：本研究开发并测试了一款用于促进糖尿病足溃疡愈合的新型系统。该系统依托其两大组件的再生特性：一款搭载天然乳胶薄片的鞋垫，以及一款内置波长635nm发光二极管（Light Emitting Diodes，LED）阵列的装置。
方法 本研究完成了电子及乳胶基装置的开发，并设置对照组（Control Group，CG）与实验组（Experimental Group，EG）开展为期4周的测试：对照组纳入5处溃疡，实验组纳入8处溃疡。对照组采用基于释银泡沫敷料的标准治疗方案，实验组则使用本次测试的新型系统进行治疗。针对每一处溃疡，我们计算了用于量化溃疡愈合百分比的指标CRU(%)：当CRU(%)=0%时代表未发生愈合，CRU(%)=100%则代表完全愈合。
结果 对照组的CRU(%)较基线实现统计学意义上的显著提升，增幅达51.8%（p=0.022），实验组的CRU(%)提升78.4%（p