SNPs associated with HbF levels in individuals with SCA in Tanzania and UK.

Abbreviations: Chr: chromosome, SNP: single nucleotide polymorphism, ref allele: ancestral allele, alt allele: alternative allele, EAF: effect allele frequency, β-value (Beta estimate): the effect that a change in single allele has on the trait,-β indicate a decreasing effect. Chromosomal position (position) given here uses hg19 co-ordinates.
SNPs associated with HbF levels in individuals with SCA in Tanzania and UK.

缩写说明：Chr：染色体（chromosome）；SNP：单核苷酸多态性（single nucleotide polymorphism）；ref allele：祖先等位基因（ancestral allele）；alt allele：替代等位基因（alternative allele）；EAF：效应等位基因频率（effect allele frequency）；β值（Beta估计值）：单个等位基因改变对性状产生的效应，带负号的β值代表该效应为性状降低。本次标注的染色体位置采用hg19坐标体系。
本数据集收录了坦桑尼亚与英国镰状细胞贫血（Sickle Cell Anemia, SCA）患者体内与胎儿血红蛋白（Hemoglobin F, HbF）水平相关的单核苷酸多态性位点。