Additional file 9 of The autophagy interaction network of the aging model Podospora anserina

Autophagy PPI network of P. anserina. This files contains the tabular representation of Fig. 3 and provides all underlying data of the constructed PPI network of autophagy. The network consists of all interactions from the prediction approach and the yeast two-hybrid analysis. It includes the ID of the interaction, the source ID, the target ID, and the score. This file also contains further information about the corresponding reference interactions. For each predicted interaction, the reference interaction from yeast and / or human with the corresponding publication, author, and interaction type is listed. In addition, the file contains the expression data which are depicted as expression profiles in Fig. 3. UniProt accession numbers were used as identifiers for proteins of yeast and human. The identifiers for P. anserina proteins were adopted from the P. anserina genome database. Species were distinguished by their NCBI taxonomy IDs: Homo sapiens (9606), Podospora anserina (5145) and Saccharomyces cerevisiae S288c (559292). (XLS 271 kb)

本数据集为羊肚柄孢壳（Podospora anserina）的自噬蛋白-蛋白相互作用（Protein-Protein Interaction，简称PPI）网络。本文件以表格形式呈现了图3的全部内容，并提供了本次构建的自噬PPI网络的所有底层数据。该网络涵盖了预测方法与酵母双杂交分析得到的全部互作关系，包含互作ID、来源蛋白ID、靶标蛋白ID及互作评分四项信息。本文件还附带了对应参考互作的补充信息：针对每一条预测得到的互作关系，均列出了来源于酵母和/或人类的参考互作，以及对应的发表文献、作者与互作类型。此外，文件包含了以表达谱形式呈现在图3中的表达数据。酵母与人类蛋白的标识符采用UniProt登录号，羊肚柄孢壳蛋白的标识符则取自其官方基因组数据库。不同物种通过NCBI分类学ID进行区分：智人（Homo sapiens）为9606、羊肚柄孢壳（Podospora anserina）为5145、酿酒酵母S288c（Saccharomyces cerevisiae S288c）为559292。本文件为XLS格式，大小271 KB。