RNA-seq identifies differential expressed genes upon YTHDC1 knockdown in MOLM13 human acute myeloid leukemia cells. RNA-seq identifies differential expressed genes upon YTHDC1 knockdown in MOLM13 human acute myeloid leukemia cells

The goal of this study is to identify differential expressed genes upon YTHDC1 depletion in MOLM13 cells(AML). Overall design: RNAs were purified from MOLM13 cells transduced with control and YTHDC1 shRNAs and then used for RNA-seq.

本研究旨在鉴定急性髓系白血病（AML）细胞系MOLM13中YTHDC1敲低后的差异表达基因。实验总体设计：从分别转染对照短发夹RNA（shRNAs）与YTHDC1靶向shRNAs的MOLM13细胞中纯化总RNA，随后将所得RNA用于RNA测序（RNA-seq）。