Whole genome sequencing of three probiotic Enterococcus faecalis strains

Some Enterococcus faecalis strains have been shown to provide beneficial effects on human and animal health. Three of those strains are contained in the probiotic drug Symbioflor1, provided by SymbioPharm (Herborn-Hoerbach, Germany). While this product is used in humans for decades without severe side effets and in this way is considered as safe, it is an essential step to ensure complete safety by evaluating their whole genomic content.

已有研究表明，部分粪肠球菌（Enterococcus faecalis）菌株可对人类与动物的健康产生有益作用。其中三株菌株被纳入由德国赫伯恩-霍尔巴赫（Herborn-Hoerbach）的SymbioPharm公司生产的益生菌药物Symbioflor1中。尽管该产品已在人类中应用数十年且未出现严重不良反应，被认为安全性良好，但通过评估这些菌株的全基因组内容以确保其完全安全性仍是必不可少的步骤。