Mantamonas mitogenome data

Here, we provide data about the mitogenome of Mantamonas sphyraenae, a protist from the deep-branching CRuMs supergroup. It contains 91 genes, including 62 protein-coding ones. These include rare homologs of the four subunits of the bacterial-type cytochrome c maturation system I (CcmA, CcmB, CcmC, and CcmF), alongside a unique ribosomal protein S6. In addition to the universally found eukaryotic mitochondrial protein import systems, the Mantamonas mitogenome encodes SecY (also found in jakobids) as well as SecA, SecE, and SecG, making it the sole eukaryote known to house a complete mitochondrial Sec translocation system. Phylogenetic and comparative genomic analyses provide compelling evidence for the alphaproteobacterial origin of this system, establishing its presence in the last eukaryotic common ancestor.

本研究提供了梭形曼塔虫（Mantamonas sphyraenae）的线粒体基因组（mitogenome）相关数据，该原生生物隶属于深度分支的CRuMs超类群。其线粒体基因组共包含91个基因，其中62个为蛋白编码基因。上述基因中包含细菌型细胞色素c成熟系统I（cytochrome c maturation system I）四个亚基的罕见同源物（分别为CcmA、CcmB、CcmC与CcmF），以及一类独特的核糖体蛋白S6（ribosomal protein S6）。除普遍存在于真核生物的线粒体蛋白导入系统外，曼塔虫的线粒体基因组还编码SecY（该蛋白同样存在于雅各巴虫属（Jakobids）物种中）、SecA、SecE及SecG，使其成为目前已知唯一拥有完整线粒体Sec转运系统的真核生物。系统发育与比较基因组学分析为该系统源自α-变形菌纲提供了有力证据，证实其存在于真核生物最近共同祖先之中。