Tumor-associated macrophages sequencing

To further explore the mechanisms by which UBC9 inhibits macrophage M1 program, TAMs from the WT and Ubc9-/- prostate tumor bearing mice were sorted for RNA sequencing.

为进一步探究UBC9抑制巨噬细胞M1型极化程序的分子机制，研究人员从野生型（Wild Type, WT）及Ubc9基因敲除（Ubc9-/-）前列腺肿瘤荷瘤小鼠体内分选肿瘤相关巨噬细胞（Tumor-associated macrophages, TAMs），并对其开展RNA测序（RNA sequencing）分析。