Validated gene fusions and rearrangements.

aGene fusions initially nominated by breakpoint analysis and subsequently validated by paired-end RNA-seq (or 5′ RACE for CEP85L/ROS1) and RT-PCR.bABL1 and EGFR locus rearrangements were previously reported in the respective cell lines [96]–[98]; however associated fusion transcripts were not identified.

本数据集所收录的基因融合（gene fusions）首先通过断点分析初步筛选得到，随后通过双端RNA测序（paired-end RNA-seq）（针对CEP85L/ROS1融合采用5'末端快速扩增技术（5' RACE））及逆转录聚合酶链式反应（RT-PCR）完成验证。ABL1与表皮生长因子受体（EGFR）基因座重排此前已在相应细胞系中被报道[96]–[98]，但未鉴定到与之相关的融合转录本。