Small cell carcinoma of the bladder

Small cell carcinoma of the urinary bladder is an extremely aggressive and rare tumor. Even though small cell carcinoma most commonly arises from the lungs there are several reports of small cell carcinoma in extrapulmonary sites. Due to its low frequency there is no well-established management for this disease. We report the case of a 61 year-old man with small cell carcinoma of the bladder who underwent radical cystectomy following neoadjuvant chemotherapy. We also reviewed the literature for the optimal treatment strategy.

膀胱小细胞癌（Small cell carcinoma of the urinary bladder）是一种极具侵袭性且极为罕见的肿瘤。尽管小细胞癌最常原发于肺部，但已有多篇报道显示肺外部位（extrapulmonary sites）也可发生小细胞癌。由于该疾病发病率较低，目前尚无公认的标准化诊疗方案。本文报告1例61岁男性膀胱小细胞癌患者，其在接受新辅助化疗（neoadjuvant chemotherapy）后行根治性膀胱切除术（radical cystectomy）。同时，本文还结合文献复习探讨了该疾病的最优治疗策略。