A Two-Part (Double-Blind Placebo Controlled/Open-Label) Multicenter Study to Evaluate Safety, Tolerability, and Efficacy of Inclisiran in Subjects With Homozygous Familial Hypercholesterolemia (Hofh) (ORION-5)

This study was a Phase III,A two-part (double-blind placebo-controlled/open-label) multicenter study to evaluate safety, tolerability, and efficacy of inclisiran in subjects with homozygous familial hypercholesterolemia (HoFH).

本研究为一项III期、两部分设计（双盲安慰剂对照/开放标签）多中心临床试验，旨在评估英克西兰（inclisiran）用于纯合子家族性高胆固醇血症（homozygous familial hypercholesterolemia, HoFH）受试者的安全性、耐受性与疗效。